1998年：Celera Genomics公司宣布测序计划

1998年5月，Celera Genomics公司成立，在三年内对大部分人类基因组进行测序。虽然该公司使用了许多HGP生成的资源，但与HGP不同，HGP在对定义的区域进行测序之前建立了详细的地图，Celera使用了霰弹枪测序策略，其中整个基因组是碎片化的，随机片段被测序，然后整理。
May 1998, the company Celera Genomics was formed to sequence much of the human genome in three years. While, the company used many HGP-generated resources, unlike the HGP, which built detailed maps before sequencing defined regions, Celera used a shotgun sequencing strategy, in which the entire genome is fragmented and random segments are sequenced and then put in order.